Browsing Bipolar Disorder by Subject "Mania"

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Mania as a possible complication of immunotherapy

Mavrotas, Myrto; Murray, Brian (2020-02)

Immunotherapy is still a relatively new cancer therapy and this article serves as a reminder to psychiatric teams to consider immunotherapy as a possible factor in psychiatric presentations. Here, the authors present the ...
A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania.

Sharpley, Ann L; Williams, Clare; Holder, Adele A; Godlewska, Beata R; Macdonald, Orla; Cowen, Philip J (2020-09)

Rationale Lithium is an effective prophylactic and anti-manic treatment in bipolar disorder; however, its use is declining through perceived poor tolerance and toxicity. Lithium inhibits inositol monophosphatase (IMPase), ...