| dc.contributor.author | Goodwin, Guy M | |
| dc.date.accessioned | 2019-03-21T13:55:43Z | |
| dc.date.available | 2019-03-21T13:55:43Z | |
| dc.date.issued | 2019-02 | |
| dc.identifier.citation | Kate Porcheret, Dalena van Heugten–van der Kloet, Guy M. Goodwin, Russell G. Foster, Katharina Wulff & Emily A. Holmes. Investigation of the impact of total sleep deprivation at home on the number of intrusive memories to an analogue trauma. Translational Psychiatry volume 9, Article number: 104 (2019) | en |
| dc.identifier.issn | 2158-3188 | |
| dc.identifier.uri | https://oxfordhealth-nhs.archive.knowledgearc.net/handle/123456789/178 | |
| dc.description | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | en |
| dc.description.abstract | Sleep enhances the consolidation of memory; however, this property of sleep may be detrimental in situations where memories of an event can lead to psychopathology, such as following a traumatic event. Intrusive memories of trauma are emotional memories that spring to mind involuntarily and are a core feature of post-traumatic stress disorder. Total sleep deprivation in a hospital setting on the first night after an analogue trauma (a trauma film) led to fewer intrusive memories compared to sleep as usual in one study. The current study aimed to test an extension of these findings: sleep deprivation under more naturalistic conditions—at home. Polysomnographic recordings show inconsistent sleep deprivation was achieved at home. Fewer intrusive memories were reported on day 1 after the trauma film in the sleep-deprived condition. On day 2 the opposite was found: more intrusive memories in the sleep-deprived condition. However, no significant differences were found with the removal of two participants with extreme values and no difference was found in the total number of intrusive memories reported in the week following the trauma film. Voluntary memory of the trauma film was found to be slightly impaired in the sleep deprivation condition. In conclusion, compared to our eariler findings using total sleep deprivation in a hospital setting, in the current study the use of inconsistent sleep deprivation at home does not replicate the pattern of results on reducing the number of intrusive memories. Considering the conditions under which sleep deprivation (naturalistic versus hospital) was achieved requires further examination. | en |
| dc.description.sponsorship | These experiments were supported by a Wellcome Trust Strategic Award [098461/Z/12/Z] to the Sleep and Circadian Neuroscience Institute (SCNi) at the University of Oxford and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre based at Oxford University Hospitals NHS Trust, Oxford University (A92181 to E.A.H., G.M.G., K.W. and R.G.F.). | en |
| dc.description.uri | https://doi.org/10.1038/s41398-019-0403-z | |
| dc.language.iso | en | en |
| dc.subject | Sleep | en |
| dc.subject | Post-Traumatic Stress Disorder (PTSD) | en |
| dc.title | Investigation of the impact of total sleep deprivation at home on the number of intrusive memories to an analogue trauma | en |
