Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal
Citation
Paul J. Harrison, Elizabeth M. Tunbridge, Annette C. Dolphin, Jeremy Hall. Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal. The British Journal of Psychiatry, 1-4 24 June 2019
Abstract
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications.
Description
Published online at: https://doi.org/10.1192/bjp.2019.157
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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