Browsing Communicable Diseases by Issue Date
Now showing items 1-13 of 13
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Sepsis recognition tools in acute ambulatory care: associations with process of care and clinical outcomes in a service evaluation of an Emergency Multidisciplinary Unit in Oxfordshire
(2018-04)Objective: To assess the performance of currently available sepsis recognition tools in patients referred to a community-based acute ambulatory care unit. Design: Service evaluation of consecutive patients over a 4-month ... -
Assessing Fluid Resuscitation in Adults with Sepsis Who Are Not Mechanically Ventilated: a Systematic Review of Diagnostic Test Accuracy Studies
(2019-05)BACKGROUND: Fluid resuscitation is a widely used intervention that is mandated in the management of sepsis. While its use can be life-saving, its overuse is associated with harm. Despite this, the best means of assessing ... -
Molecular and antibody point-of-care tests to support the screening, diagnosis and monitoring of COVID-19
(2020-04)Moving diagnostic testing for COVID-19 from laboratory settings to the point of care is potentially transformative in the rate and quantity of testing that could be performed. Eleven diagnostic tests that are potentially ... -
Physical activity in a pandemic: A new treatment target for psychological therapy.
(2020-06)The COVID-19 pandemic and its management are placing significant new strains onpeople’s well-being, particularly those with pre-existing mental health conditions. Physicalactivity has been shown to improve mental as well ... -
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
(2020-07)Background The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be curtailed by vaccination. We assessed the safety, reactogenicity, and immunogenicity of a viral vectored coronavirus vaccine ... -
An invasive group A streptococcal infection outbreak: a community nursing experience
(2020-07)Invasive group A streptococcus (iGAS) can cause serious infections. Between January and July 2018, seven patients, living in the same geographical area and receiving district nursing care for wound management, were identified ... -
Will COVID-19 be the coming of age for point-of-care testing?
(2020-09)BACKGROUND As countries deal with the COVID-19 pandemic in varying ways, one area of agreement is the need to test for the COVID-19 virus in as many people as possible. Beeching et al have rightly pointed out that ... -
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
(2020-12)Background Older adults (aged ≥70 years) are at increased risk of severe disease and death if they develop COVID-19 and are therefore a priority for immunisation should an efficacious vaccine be developed. Immunogenicity ... -
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
(2020-12)More than 190 vaccines are currently in development to prevent infection by the novel severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while neutralizing antibodies against the viral spike protein ... -
Harnessing the nursing contribution to COVID-19 mass vaccination programmes: Addressing hesitancy and promoting confidence
(2021-04)The need for a mass vaccination programme for COVID-19 is considered a pivotal public health strategy to reduce rates of infection, hospitalizations and deaths which have been so much a feature of the past year of the ... -
Online Social Endorsement and Covid-19 Vaccine Hesitancy in the United Kingdom
(2021-04)We explore the implications of online social endorsement for the Covid-19 vaccination program in the United Kingdom. Vaccine hesitancy is a long-standing problem, but it has assumed great urgency due to the pandemic. By ... -
“It seems impossible that it’s been made so quickly”: a qualitative investigation of concerns about the speed of COVID-19 vaccine development and how these may be overcome
(2022-02)The speed of COVID-19 vaccine development has been identified as a central concern contributing to hesitancy in acceptance. We conducted qualitative interviews to gain a greater understanding into these concerns and to ... -
The Disease Influenced Vaccine Acceptance Scale-Six (DIVAS-6): Validation of a Measure to Assess Disease-Related COVID-19 Vaccine Attitudes and Concerns
(2022-06)Patients with underlying comorbidities are particularly vulnerable to poor outcomes from SARS-CoV-2 infection. Despite the context-specific nature of vaccine hesitancy, there are currently no scales that incorporate disease ...