Browsing Conducting Research by Title
Now showing items 1-20 of 49
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Adding value, reducing research waste, the role of the NHS research and development management community
(2018-02-23)Purpose – Research suggests that 85 per cent of health research is avoidably wasted. The research and development management community has an important role in the research process and can contribute to improving the ... -
The Africa Ethics Working Group (AEWG): a model of collaboration for psychiatric genomic research in Africa [version 1; peer review: awaiting peer review]
(2021-07)The Africa Ethics Working Group (AEWG) is a South-South-North collaboration of bioethics and mental health researchers from sub-Saharan Africa, working to tackle emerging ethical challenges in global mental health research. ... -
Applying the triple bottom line of sustainability to healthcare research—a feasibility study
(2019-05)The triple bottom line (TBL) of sustainability is an important emerging conceptual framework which considers the combined economic, environmental and social impacts of an activity. Despite its clear relevance to the ... -
Barriers and incentives to recruitment in mental health clinical trials
(2019-05)Research provides valuable information that improves patients’ outcomes and should inform clinical decision-making.1 There are many research methodologies2 and randomised controlled trials (RCTs) are at the top of the ... -
Burden of cancer trial participation: A qualitative sub-study of the INTERIM feasibility RCT
(2021-11)A qualitative sub-study was carried out within a larger phase II feasibility trial, to identify and describe the burden experienced by advanced melanoma patients participating in a clinical trial and the factors affecting ... -
Can rapid approaches to qualitative analysis deliver timely, valid findings to clinical leaders? A mixed methods study comparing rapid and thematic analysis
(2018-08)Objectives: This study compares rapid and traditional analyses of a UK health service evaluation dataset to explore differences in researcher time and consistency of outputs. Design: Mixed methods study, quantitatively ... -
Co-producing Human and Animal Experimental Subjects: Exploring the Views of UK COVID-19 Vaccine Trial Participants on Animal Testing
(2021-11)Preclinical (animal) testing and human testing of drugs and vaccines are rarely considered by social scientists side by side. Where this is done, it is typically for theoretically exploring the ethics of the two situations ... -
Co-Production: An Ethical Model for Mental Health Research?
(2019-07)Commentary arguing for involving people with a diagnosis of mental health disorders and/or their caregivers as co-researchers in mental health research. -
Collecting self-report research data with people with dementia within care home clinical trials: Benefits, challenges and best practice
(2019-08)One-third of people with dementia live in care home settings and in order to deliver better evidence-based care, robust research including clinical trials is required. Concerns have been raised by researchers about the ... -
Combining Pharmacological and Nonpharmacological Interventions in Network Meta-analysis in Psychiatry
(2019-04)Network meta-analyses (NMAs) assess the comparative associations of 2 or more interventions even if they have not been compared in a randomized clinical trial.1 The validity of NMAs is founded on the assumption of transitivity ... -
Consent to discuss participation in research: a pilot study
(2019-09)Background. Equitable access to research studies needs to be increased for all patients. There is debate about which is the best approach to use to discuss participation in research in real-world clinical settings. Objective. ... -
Co‐producing research with youth: The NeurOx young people’s advisory group model
(2019-03)Context: The 1989 UN Convention on the Rights of the Child states that children have the right to be heard in all matters affecting them. The Convention inspired a surge in research that investigates young people's ... -
Dealing with categorical risk data when extracting data for meta-analysis
(2021-01)A common problem in meta-analysis of observational studies arises when the exposure variable is categorical rather than continuous. These data may be referred to as quantile or quintile data (depending on the number of ... -
Development of A Guideline for Reporting Mediation Analyses (AGReMA)
(2020-02)There are a growing number of studies using mediation analysis to understand the mechanisms of health interventions and exposures. Recent work has shown that the reporting of these studies is heterogenous and incomplete. ... -
Difficult conversations? Engaging patients in reducing waste in health care
(2016)Purpose – Reducing waste in health care can result in savings that could be used to meet the projected shortfall in NHS funding or to meet the care needs of vulnerable groups. Patients and their families can contribute ... -
Estimating and visualising the trade-off between benefits and harms on multiple clinical outcomes in network meta-analysis
(2023-11)The relative treatment effects estimated from network meta-analysis can be employed to rank treatments from the most preferable to the least preferable option. These treatment hierarchies are typically based on ranking ... -
Ethical challenges in Research, Industry and People Partnerships in mental health
(2020-08)Advancements in mental health research, social changes and policy developments have led to the emergence of new forms of research partnerships, which bring together research institutions, public companies and lay people ... -
Ethical implications of poor comparative effectiveness evidence: obligations in industry-research partnerships
(2020-03)Which treatment is best for me? This question is at the centre of the clinical consultation. And yet, too often, the question is not answerable with available evidence on drugs and devices. The two Lancet Series papers on ... -
Ethical Issues in Consent for the Re-use of Data in Health Data Platforms
(2020-12)Data platforms represent a new paradigm for carrying out health research. In the platform model, datasets are pooled for remote access and analysis, so novel insights for developing better stratified and / or personalised ... -
Extracting data from diagnostic test accuracy studies for meta-analysis
(2021-01)It is important that DTA reviews summarise all the available evidence. Studies in which the necessary information is not fully reported should not necessarily be excluded from pooled analyses. As reported in this article, ...
