Browsing Mental Disorders (General) by Issue Date
Now showing items 1-20 of 57
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The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis
(2017-09-06)Summary: Background Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether ... -
Time to focus more on promoting mental health than treating mental illness
(2018-03)Mental health problems are a major contributor to overall burden of disease worldwide. In UK, it represents up to 23% of the total burden of disease - the largest single cause of disability. To build a healthier, more ... -
The times they are a-changin’
(2018-07)Editorial: "The first issue of Evidence-Based Mental Health (EBMH) is celebrating the 20th anniversary. Readers were welcomed to EBMH in 1998, which was designed to assist ‘mental health clinicians stay up to date with the ... -
The effect of a youth mental health service model on access to secondary mental healthcare for young people aged 14–25 years
(2018-09)Aims and method The Norfolk Youth Service was created in 2012 in response to calls to redesign mental health services to better meet the needs of young people. The new service model transcends traditional boundaries by ... -
The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function
(2019)Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ... -
The Functional Consequences of Social Attention for Memory-guided Attention Orienting and Anticipatory Neural Dynamics
(2019-02)Social attention when viewing natural social (compared to non-social) images has functional consequences on contextual memory in healthy human adults. In addition to attention affecting memory performance, strong evidence ... -
The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
(2019-02)Background: The discovery that voltage-gated calcium channel genes such as CACNA1C are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic potential of L-type calcium channel (LTCC) ... -
Variation in spend on young mental health across Clinical Commissioning Groups in England: a cross-sectional observational study
(2019-08)Objectives To investigate whether the rate of spend on child and adolescent mental health is influenced by demand for other competing services in local commissioning decisions. Design Analysis of spend data by Clinical ... -
Supported decision making for people with mental health disorders in clinical practice: a systematic review.
(2019-10)Objectives: The Convention on the Rights of Persons with Disabilities (CRPD) was adopted at the United Nations Assembly in 2006. The main aim of the convention is to ensure equal rights for people with disabilities including ... -
Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA
(2020)Background Adverse mental health consequences of COVID-19, including anxiety and depression, have been widely predicted but not yet accurately measured. There are a range of physical health risk factors for COVID-19, but ... -
Supporting people in mental health crisis in 21st-century Britain
(2020-02)Recent years have seen a surge in interest in mental healthcare and some reduction in stigma. Partly as a result of this, alongside a growing population and higher levels of societal distress, many more people are ... -
Five models for child and adolescent data linkage in the UK: a review of existing and proposed methods
(2020-02)Over the last decade dramatic advances have been made in both the technology and data available to better understand the multifactorial influences on child and adolescent health and development. This paper seeks to ... -
Unraveling Mechanisms of Patient-Specific NRXN1 Mutations in Neuropsychiatric Diseases Using Human Induced Pluripotent Stem Cells
(2020-03)Rare heterozygous deletions in the neurexin 1 (NRXN1) gene robustly increase an individual's risk of developing neurological and psychiatric disorders. However, the molecular bases by which different mutations result in ... -
Covid-19 and mental health: a transformational opportunity to apply an evidence-based approach to clinical practice and research
(2020-04)The Oxford Precision Psychiatry Lab (https://oxfordhealthbrc.nihr.ac.uk/our-work/oxppl/, @OxfordPPL) collected from senior clinicians in the local Mental Health Trust a list of specific and focused questions about mental ... -
Cognitive Performance, Quality and Quantity of Movement Reflect Psychological Symptoms in Adolescents
(2020-05)The presentation of unhealthy psychological symptoms are rising sharply in adolescents. Detrimental lifestyle behaviours are proposed as both possible causes and consequences. This study set out to compare selected ... -
Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/ hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects
(2020-06)Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental disorders in this age group and are used not infrequently off‐label. However, ... -
What does COVID mean for UK mental health care?
(2020-06)The coronavirus disease (COVID) pandemic is the biggest disaster United Kingdom has seen for many decades. Not since World War II has there been such risk, displacement and change affecting the whole community. This is the ... -
COVID-19, mental health and ethnic minorities
(2020-07)There is little formal guidance for the busy clinician in balancing different risks for individual mental health patients and treating appropriately. To fill this gap, we propose three core actions that may help: 1. ... -
7 Virtual reality (VR) for the treatment of mental health disorders
(2020-07)Mental health disorders are very common, but far too few people receive the best treatments. Much greater access to the best psychological treatments may be achieved using automated delivery in virtual reality (VR). With ... -
Advances in the computational understanding of mental illness
(2020-07)Computational psychiatry is a rapidly growing field attempting to translate advances in computational neuroscience and machine learning into improved outcomes for patients suffering from mental illness. It encompasses both ...
